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Realizing the potential of gene therapy for neurological disorders

Promising findings from preclinical animal studies show the potential of gene therapy for treating incurable neurological disorders. Scientists have successfully used gene therapy to slow the progression and improve symptoms of disorders such as amyotrophic lateral sclerosis and Parkinson’s disease. from Parkinson’s News — ScienceDaily https://ift.tt/2SMiCUN

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Cooling ‘brains on fire’ to treat Parkinson’s

A promising new therapy to stop Parkinson’s disease in its tracks has been developed by scientists who found that a small molecule, MCC950, stopped the development of Parkinson’s in several animal models. The team hope to commence human clinical trials in 2020. from Parkinson’s News — ScienceDaily https://ift.tt/2qqaRHf

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Appendix identified as a potential starting point for Parkinson’s disease

Removing the appendix early in life reduces the risk of developing Parkinson’s disease by 19 to 25 percent, according to the largest and most comprehensive study of its kind. The findings solidify the role of the gut and immune system in the genesis of the disease, and reveal that the appendix acts as a major reservoir for abnormally folded alpha-synuclein…

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Regulating microglial activity may reduce inflammation in neurodegenerative diseases

A group of investigators is proposing that targeting immune checkpoints — molecules that regulate the activity of the immune system — in immune cells called microglia could reduce the inflammatory aspects of important neurodegenerative diseases like Alzheimer’s disease, Parkinson’s disease and ALS. from Parkinson’s News — ScienceDaily https://ift.tt/2NQLnw4

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Diagnosing types of fear of falling in Parkinson’s patients

Parkinson’s disease causes one of the highest risks of falling among all neurological conditions. Due to this, many patients develop a fear of falling, even if they’ve never fallen. Researchers have discovered a way to diagnose subtypes of fear of falling in hopes of improving treatment and quality of life for patients. from Parkinson’s News — ScienceDaily https://ift.tt/2ORkh94