Researchers Evaluate Computer-based Therapy to Ease Fatigue, Improve Motor Function

An ongoing pilot trial is evaluating a computer-based, non-pharmacological cognitive approach to improve motor function and ease fatigue in people with Parkinson’s disease. “Study protocol for a randomised pilot study of a computer-based, non-pharmacological cognitive intervention for motor slowing and motor fatigue in Parkinson’s disease,” appeared in the journal Pilot and Feasibility Studies. Non-pharmacological therapies may

Biogen, C4 Therapeutics Working to Treat Parkinson’s by ‘Naturally’ Degrading and Clearing Proteins

Biogen and C4 Therapeutics (C4T) have joined efforts to develop therapies using a cell’s natural protein degradation system as a way of treating neurological diseases such as Alzheimer’s and Parkinson’s. This agreement allows the two to combine Biogen’s expertise in neuroscience and therapy development with C4T’s knowledge and research work into targeted protein degradation, or

Advanced PD and Palliative Care in the 21st Century

1.What is Palliative Care? 2.The Care Team Role 3.Managing Pain 4.Reducing Side Effects        5.Planning Advance Care 6.Conclusion Advanced PD and Palliative Care in the 21st Century Palliative care is a holistic, team-based approach to managing chronic health conditions, such as Parkinson’s disease (PD). Palliative care specialists champion quality of life and can be central to navigating

Parkinson’s Patients and Caregivers are Active, but Lack Self-management Support, Study Finds

Patients with Parkinson’s disease and their caregivers are usually active and ready to adopt strategies to improve their quality of life and disease management, but lack self-management support, a study finds. The study, “Development of the Integrated Parkinson’s Care Network (IPCN): using co-design to plan collaborative care for people with Parkinson’s disease,” was published in

Changes in Innate Immunity, Cell Waste Disposal Process Linked to Loss of Dopaminergic Neurons in Early Study

Together with aging, the disruption of a cell’s waste disposal system and exaggerated immune responses can lead to the progressive loss of dopamine-producing neurons seen in diseases like Parkinson’s, according to new research in fruit flies. The study, “Hyperactive Innate Immunity Causes Degeneration of Dopamine Neurons upon Altering Activity of Cdk5,” was published in the journal

Wireless Pacemaker-like Device May Offer Real-time Treatment for Parkinson’s, Study Reports

A new neuromodulator — a wireless pacemaker-like device — may provide real-time treatment to patients with diseases such as Parkinson’s by monitoring abnormalities and delivering corrective electrical signals to the brain. The device was described in the study, “A wireless and artefact-free 128-channel neuromodulation device for closed-loop stimulation and recording in non-human primates,” published in

A New Year’s Resolution: Quiet the Old Tapes

In my column about time management, I mentioned a nagging inner voice saying, “You did not get enough done today.” That phrase ties to an old “tape,” inner dialogue left by the voices of parents and childhood teachers that says, “You are never going to amount to anything. You are a bad person.” The inner drive

Engineered Stem Cells Could Be Next Parkinson’s Treatment, Researchers Say

Cutting out a portion of or removing a gene linked to Parkinson’s disease protects against the formation of toxic protein clumps within brain cells, scientists have found. This discovery has the potential to significantly affect the development of next-generation cell-based therapies, which involve injecting healthy cells into brain regions already affected by the disease. Researchers