Research

Russian Researchers Create Software that Predicts Parkinson’s Symptoms

A new software can predict with an accuracy of 96 percent the form of Parkinson’s disease and future symptoms that a patient may experience. The software was the result of a collaboration between researchers at Peter the Great St. Petersburg Polytechnic University (SPbPU), the Institute of Experimental Medicine, and ITMO University, in Russia. This technology may improve early diagnosis, promote…

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British Crew Rowing the Distance to Improve Understanding of Parkinson’s Disease

A four-man crew from Britain is hoping to increase understanding of Parkinson’s disease by rowing across the Indian Ocean in an attempt to break a world record. Robin Buttery, Barry Hayes, James Plumley, and skipper Billy Taylor are planning to row for 1,920 hours non-stop, for 65 days straight, all the way from West Australia to Mauritius, with the goal of becoming the fastest…

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Sunovion’s Oral Apomorphine Film Seen to Ease Parkinson’s Off Periods in Phase 3 Trial

Sunovion Pharmaceuticals’ apomorphine sublingual under-the-tongue film (APL-130277) — now under review for approval —  significantly improved motor fluctuations, or off episodes, in Parkinson’s patients in Phase 3 clinical trial, results show. The double-blind pivotal study, (NCT02469090), evaluated the efficacy and safety of APL-130277 as a fast-acting oral treatment for Parkinson’s patients with off periods, including those experiencing early morning off episodes. These episodes…

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Deep Brain Stimulation May Increase Levels of Inflammatory Factors in Parkinson’s, Study Suggests

Deep brain stimulation (DBS) may increase the levels of hepcidin — a hormone associated with iron accumulation and inflammation in the brain — in Parkinson’s disease patients, according to a small Polish study. The study, “Higher serum levels of pro-hepcidin in patients with Parkinson’s disease treated with deep brain stimulation,” was published in the journal Neuroscience Letters. As people age,…

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Safer Way of Stimulating Neural Stem Cells for Therapies and Research Developed

A new device that can increase the production of viable neural stem cells may change the landscape of neural stem cell therapies as potential strategies for neurodegenerative and chronic diseases, including Parkinson’s and Alzheimer’s. The invention, developed by a team at Hong Kong Baptist University (HKBU), was recently awarded with the Gold Medal with Congratulations of Jury at the 46th International…

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FDA Grants Regenerative Medicine Advanced Therapy Designation to VY-AADC for Parkinson’s

The U.S. Food and Drug Administration granted Voyager Therapeutics’ gene therapy candidate VY-AADC regenerative medicine advanced therapy (RMAT) designation for the treatment of therapy-resistant motor fluctuations in Parkinson’s patients. The RMAT designation, recently created by the FDA, is given to regenerative medicine products intended to treat, modify, reverse, or cure a serious or life-threatening disease or condition, and that have early…

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The ABCs of Parkinson’s Disease: The Letter B

Second in a series. Read part one. The letter B is for balance and Botox. Balance Many people with Parkinson’s experience walking or balance problems, which can occur in differing degrees. Gait problems can range from the disease slowing your speed, to a lessening of your arm swing and steps that tend to mimic shuffling instead of having a regular…

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Dopamine Agonists Linked to Impulse Control Disorders in Parkinson’s Patients, Study Finds

More than half of Parkinson’s patients who have been treated with a dopamine agonist may develop impulse control disorders over time, according to recent research. The study, “Longitudinal analysis of impulse control disorders in Parkinson disease,” was published in the journal Neurology. Impulse control disorders are characterized by the inability to resist impulses or to control specific behaviors. These include compulsive…

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Michael J. Fox Foundation Summit Outlines Next Steps in Search for Parkinson’s Cure

The Michael J. Fox Foundation (MJFF) recently held a summit to discuss the unmet needs and challenges for advancing therapies to slow down or halt Parkinson’s disease. The event, which took place in New York, was attended by representatives from 20 companies, a number of academic centers and research organizations, and the U.S. Food and Drug Administration. Some of the points discussed during…

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