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Become a Parkinson’s Care Advocate: Join Our Aware in Care Ambassador Pilot Program

When hospitalized, three out of every four people with Parkinson’s disease (PD) do not receive their medications on time. Most develop serious complications as a result. In 2011, the Parkinson’s Foundation launched Aware in Care to help people with Parkinson’s get the best care possible during a hospital stay, and it worked. Surprisingly, 70% of hospital staff are still unaware of…

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The ABCs of Parkinson’s: ‘K’ Is for Knowledge

A continuation of the “ABCs of Parkinson’s” series. When diagnosed with Parkinson’s disease (PD), or any disease, it is always beneficial to educate yourself about it. Ask yourself: Do they know what caused it? What are the symptoms? How can I best care for myself? Is there a cure? Knowledge is a good and powerful thing. However, too much knowledge…

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Dopamine Depletion Not Associated with Non-motor Symptoms in Key Parkinson’s Brain Area, Study Shows

Dopamine depletion in a brain region called the striatum does not correlate with the severity of non-motor symptoms in patients with Parkinson’s disease, according to a new imaging study. The research, “Lack of association between dopamine transporter loss and non-motor symptoms in patients with Parkinson’s disease: a detailed PET analysis of 12 striatal subregions,” was published in the journal Neurological…

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Analysis of Tiny Vesicles Released by Red Blood Cells May Help Identify Parkinson’s Patients, Study Shows

A new blood-based analysis that evaluates the levels and content of tiny vesicles released by red blood cells may help diagnose patients with Parkinson’s disease according to disease stage, researchers suggest. The new method was described in the study, “Portrait of blood-derived extracellular vesicles in patients with Parkinson’s disease,” published in Neurobiology of Disease. Parkinson’s disease is linked to a broad…

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Arranging for My Brain Donation Was an Arduous Process

Why is there no cure for PD? In my mind, there are several potential reasons there is no cure for Parkinson’s disease (PD). The brain is an extremely complex organ and there is no known definitive cause for the disease. Each PD diagnosis is unique, patients suffer different symptoms and different rates of disease progression, and certain remedies work for…

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PIG3 Protein’s Role in Development of Familial Parkinson’s Detailed in Studies

Results from preclinical studies show the PIG3 protein as a key player in LRRK2-mediated familial Parkinson’s disease. The findings were discussed in two presentations at the Society for Neuroscience (SfN) 2018 annual meeting in San Diego, California. Mutations in the LRRK2 gene — the leading genetic cause of Parkinson’s — account for about 1 to 2 percent of all disease cases. LRRK2 codes for the…

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How 2 Proteins Affect Pathway Linked to Early Onset Disease Detailed for Possibly 1st Time

The significance — physiological and clinical — in the interaction of two proteins known to be associated with early onset Parkinson’s disease, PARKIN and PINK1, is detailed, possibly for a first time, by researchers. Their study, “Phosphorylation of Parkin at serine 65 is essential for its activation in vivo,” was published in the journal Open Biology. Mutations in the genes…

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Most Untreated Parkinson’s Patients Have Non-Motor Symptoms, Study Shows

Non-motor symptoms are common among patients with Parkinson’s disease who have not yet received any treatment, and the type of symptoms differs between men and women and onset age groups, a study shows. The study, “Gender and onset age related-differences of non-motor symptoms and quality of life in drug-naïve Parkinson’s disease,” was published in the journal Clinical Neurology and Neurosurgery.…

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How to Get Through the Cold of Winter

Winter has just about landed upon us, and it’s getting to be that time of year when we hang up garden tools, freeze-proof the outside water spigots, and pull out the heavy sweaters and rain boots. For many of us, it also means trying to get warm and comfortable with our Parkinson’s disease while freezing as we watch the snow…

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Phase 3 Trial of Accordion Pill in Treating Parkinson’s ‘Off’ Periods Fully Enrolled

Intec Pharma announced the complete enrollment of a Phase 3 clinical trial evaluating the safety and effectiveness of its Accordion Pill Carbidopa/Levodopa (AP-CD/LD) in easing motor fluctuations in people with advanced Parkinson’s disease. The investigative treatment will be compared to immediate release Sinemet, an approved combination of levodopa and carbidopa marketed by Merck, and to placebo in the study. Levodopa is considered the most effective…

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